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Objectives: To present an unusual complication related to prolonged ECMO support in a patient with COVID19 induced acute respiratory syndrome (ARDS). Method(s): Clinical chart review of the care process after obtaining the informed consent from the patient. Result(s): A 48-year-old female with COVID-19 infection during second wave of pandemic in August 2021 progressed to severe ARDS. She was put on VV-ECMO support after failing conventional therapy for refractory hypoxemia. Her cannulation configuration included a 25 F venous drainage cannula in the right femoral vein and a 21 F venous return cannula in the right Internal Jugular (IJ) vein. Cannulations were performed using the ;Seldinger technique;under USG guidance, and no difficulties or complications were reported. Her hospital course was notable for delirium, and intermittent bleeding from the cannula sites. After 80 days of support, she showed adequate respiratory improvement which allowed ECMO decannulation. She continued to show improvement, and was eventually discharged after 102 days of total hospital stay. During her 6 weeks follow-up clinic visit a palpable thrill was noted at the jugular ECMO cannula site. A CT angiogram of the neck demonstrated a large venous varix connecting the right IJ and the left common carotid artery with filling from the left common carotid artery. ECMO cannulation site complications such as aneurysm, clots, infections and stenosis are well known. What was unusual in this case is the nature of the aneurysm given that there were no arterial procedures performed on the left side of the neck. She was managed by an ;Amplatzer plug;to the carotid artery at the level of the connection to the varix without any complications. Conclusion(s): Longer duration of ECMO support needs careful follow-up for timely recognition and management of vascular complications. (Figure Presented).
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Objectives: More than 200 patients have benefited from lung transplantation who failed to recover from COVID-19-induced acute respiratory distress (ARDS) with conventional ventilatory support and/ or extracorporeal membrane oxygenation support (ECMO) in USA. We aim to share our experience and lessons learned at our institute through this case series. Method(s): After IRB approval, we performed a retrospective chart review and identified 37 patients who received ECMO for COVID-19 induced ARDS between May 2020 through January 2022. Out of these, 12 received a formal consultation from the transplant team. We studied patient characteristics, interventions during ECMO support, and evaluation outcomes. Result(s): Most of our patients had single organ failure i.e., lung, except for two who required dialysis after ECMO initiation. Six out of the 12 patients received bilateral lung transplant. One patient received the transplant before ECMO initiation. However, the patient required two runs of ECMO after the transplant due to postop complications from suspected COVID19 reinfection and deceased on postoperative day 101. All the patients after transplant had an expedited recovery except one who required prolonged hospitalization before starting physical therapy. The median length of hospital stay for the transplant group was 148 (89- 194) days and for the non-transplant group was 114 (58-178) days. The 30-day survival rate was 100% for the transplant group. At a median follow-up of 207 (0- 456) days after discharge, 5(83.3%) patients in the transplant group and 3(50%) patients in the nontransplant group were alive. In the non-transplant group, 4 patients received ECMO support for more than 75 days and at last follow-up 2 were alive and functioning well without needing new lungs. This asks for an objective prospective study to define the timeline of irreversibility of the lung injury. Conclusion(s): Lung transplantation is a viable salvage option in patients with COVI-19 induced irreversible lung injury. However, the irreversibility of the lung injury and the timing of lung transplant remains to be determined case-by-case. (Figure Presented).
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Worldwide, infectious diseases have contributed significantly to morbidity and mortality;among the leading causes of death are pneumonia, respiratory infections and Covid-19. Stem cell therapy will be used to treat virus-infected patients in an effective and safe manner. A cross-sectional questionnaire was used to collect data from doctors. Most doctors are aware of the applications of stem cells, but they do not confirm their usage because clinical trials are ongoing. Instead, they show support for using stem cells to treat patients. Stem cells have been hoping to help repair damaged tissues in the respiratory system to promote faster recovery. Stem Cells are being studied in current clinical trials for their efficacy and safety in virus severe pneumonia and respiratory infections. The doctors suggested that stem cells have been used in infectious diseases to improve their health.Copyright © 2023 Health Biotechnology And Biopharma. All rights reserved.
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Objectives: Extracorporeal membrane oxygenation (ECMO) is well established in cardiorespiratory failure. Here we report the use of ECMO in an airway emergency to provide respiratory support. Method(s): Informed consent was obtained from patient at the time of admission. Result(s): A 48-year-old with COVID-19 requiring venovenous ECMO (VVECMO) for 32 days and tracheostomy for 47 days had developed tracheal stenosis three months after tracheostomy removal, and undergone tracheal resection and reconstruction. He presented two weeks later with acute dyspnea, bloody drainage and a bulge in his neck with coughing. A computerized tomography (CT) of the cervical spine and chest showed dehiscence of the tracheal wound and a gap in the trachea. He was managed with High Flow Nasal Canula and supported on VVECMO support using 25 Fr. right femoral drainage cannula and 23 Fr. left IJ return cannula. A covered stent was placed, neck wound was irrigated and debrided. Patient was decannulated after 10 days on ECMO. Future therapeutic considerations include mediastinal tracheostomy, aortic homograft interposition of the disrupted segment of trachea with stent placement and permanent self-expandable stent with internal silicone stent. Conclusion(s): ECMO is increasingly used in complex thoracic surgery as well as in the perioperative period as salvage support. One of the areas where it has shown promising results is traumatic main bronchial rupture, airway tumor leading to severe airway stenosis, and other complex airway problems. The ease of cannulation, the technological advances and growing confidence in the management of ECMO patients are the main reasons for the expansion of ECMO use beyond conventional indications. The case described above is an example of the use of ECMO in the perioperative management of impending respiratory failure due to airway obstruction or disconnection. (Figure Presented).
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This research aims to check the chargeability of sodium hypochlorite and the efficacy evaluation of an air-assisted electrostatic disinfection device. Five different inanimate surfaces i.e., wood, glass, stainless steel, plastic and fabric were considered to examine the performance in terms of efficacy, survival time, off-target losses, spray coverage and the volume of disinfectant consumed. A significant charge-to-mass level of 2.43 mC/kg was achieved for sodium hypochlorite at an applied voltage of 2.0 kV, a liquid flowrate of 253 ml/min and applied air pressure of 4.0 bar. The experimental results found that 1000 mg/L of sodium hypochlorite concentration effectively eliminated Pseudomonas aeruginosa, Clostridium perfringens and Bacteriophage MS2 colonies. © 2023 Elsevier B.V.
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COVID-19 pandemic affected the entire globe in 2019. This pandemic is considered as the first one with its defense more than pharmaceutical measures such as: Personal hygiene (hand sanitization, wearing masks) and social distancing. This pandemic has affected people with different factors such as: anxiety, emotions, social life, mental and physical health, and economic crisis. These factors helped this pandemic to turn up with digital solutions for its prevention and prediction estimation. These prediction techniques can analyze the previous data set of this pandemic and provide interesting insights about such a situation to occur in future along with its prevention measures. In this article, we tried to systematize various research activities-using machine learning, data science, and data visualization to extract meaningful information about COVID-19. Data collection has been done by conducting open surveys on different platforms such as: social media, university survey as well as community survey. Based on the collected data, analysis has been done on the emotional, social and mental health of people in order to provide future research directions and collective fight against such pandemics. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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The COVID-19 pandemic has forced most interactions to move to online space, starting from online lectures, conferences in hybrid mode, and work-from-home office works. Hence, it is essential for live video streaming to be reliable and provide a good quality of experience (QoE) to users. However, in large sections of the world, the cellular network is not reliable enough to be used for online participation in such events. To quantify this problem, we first measure the QoE in terms of lag, video resolution, and dropped calls on a popular video conferencing platform Google Meet over three different cellular ISPs in New Delhi, India. We observe significantly worse quality of experience metrics compared to a study recently performed in the US. To mitigate this problem, we propose NATIVE (Network Aggregation-based Tiled lIve Video strEaming), a system of aggregating the cellular network connectivity using a secondary or helper device in the vicinity trusted by the user. The implementation of NATIVE uses tiled encoding of video, where the video frames are divided into rectangular units known as tiles. All the tiles are divided into two subsets which are scheduled independently via the available network interfaces depending on its importance. The receiver device receives video segments from the two network paths and stitches back the tiles in them to play. We show the demo of NATIVE using two laptops and a cloud server where the server acts as a streamer. © 2023 IEEE.
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Climate change threatens population health in multiple ways. In 2018, 220 million older adults were exposed to heatwaves, a top cause of direct climate-related deaths, than in 2000. If there were doubts about the need to urgently strengthen public health systems worldwide to prepare for climate change, the coronavirus disease 2019 (COVID-19) pandemic has dispelled them. Researchers have been concerned for decades about the potential for global warming to support conditions for infectious disease outbreaks and to amplify other health impacts associated with heat, drought, storms, and related hazards. Risks related to these direct and indirect climate impacts are increasing around the world;they are becoming particularly acute in Asia and Africa and in urban areas more generally. Prominent voices have urged building health system preparedness and resilience to these climate-related threats. Yet chronic underfunding has plagued national and local public health agencies across many parts of the world. Only 5% of international spending for climate adaptation is directed toward public health, and health agencies are often poorly integrated into climate change planning. While the critical task at hand is turning the tide on COVID-19, this pandemic serves as a clarion call to governments and citizens alike to ensure public health systems are better prepared to meet the emergencies of the future, many of which will be climate-related. This paper also discuss the framework for building blocks of resilient health care systems and case study of Corona Resilient forum during COVID-19 in Bihar. © 2023 DMICS.
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Background: Health-care providers, particularly pediatric dentists, highly depend on electronic media. This survey attempts to assess how they have taken to e-media to keep themselves abreast of the current situation and use it efficiently. Objectives: To determine attitudes, awareness, and practices of e-media usage among pediatric dental professionals and postgraduate students in pediatric dentistry during the COVID-19. Materials and Methods: A convenience sample of 958 pediatric dental practitioners and postgraduate students in pediatric dentistry from throughout India participated in a descriptive cross-sectional survey. An investigator-designed questionnaire comprising 23 close-ended questions related to the usage and various aspects of e-media before and during the COVID-19 pandemic. Results: Younger generations of pediatric dentistry are more active in the use of e-media. Dentists between the ages of 30 and 50 years are more likely to utilize social media in their profession than dentists above the age of 50 years. For academic purposes and patient communication, e-media was the most popular choice. Conclusion: The Indian pediatric dentistry profession has grown significantly with the use of e-media. © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
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Purpose: COVID-19 pandemic has overturned the work and family life challenging the world in unpredictable ways that were previously unimaginable. With universities shutting down and emergence of online classes, this phenomenon is prevalent among academicians as well. With this background, the current study aims to investigate the direct relationships between workplace isolation (WPI) during COVID-19 and work–family conflict (WFC) with psychological stress (PS) mediating and organizational identification (OI) moderating the relationship between the two. Design/methodology/approach: The authors employed time lagged survey and collected data at three different time intervals (T1, T2, T3) from 203 academicians working across various universities and colleges in India. The data were analyzed quantitatively using SPSS PROCESS Macro and AMOS. Findings: The results indicated that WPI during COVID-19 has a significant positive relationship with PS and WFC. It was also found that PS partially mediated the relationship between WPI during COVID-19 and WFC. Further, OI emerged as a potential moderator. Originality/value: Based on the current empirical studies, it remains unclear if WPI during COVID-19 is associated with WFC. Therefore, drawing upon stress–strain–outcome (SSO) model and the conservation of resource theory, this study makes a significant contribution to the existing body of literature by exploring the unexplored associations. To the best of the authors' knowledge, such an association has not received much scholarly attention before. © 2023, Emerald Publishing Limited.
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Purpose: The on-going pandemic has impacted the use of anesthesia and the operating room frequency thereby affecting the brachytherapy treatment in various institutions due to the COVID-19 protocols. This has led to single applications of Intracavitary brachytherapy (ICRT) being used to deliver entire treatment boost in cervix cancer. We present our dosimetric and early clinical outcomes comparing traditional weekly three-fractions ICRT with single application/ two-applications ICRT Material(s) and Method(s): In this retrospective analysis conducted in our department, a total of 39 cases, treated between January 2021 to January 2022 were evaluated for the study. Of these, 15 cases were treated with the traditional once a week applicator insertion for 3 fractions and 24 cases underwent lesser application - 20 cases underwent 2 insertions and 4 cases single insertion (all receiving total 3 fractions of 7Gy each). The dosimetric parameters were compared including CTV D90 and D95 along with rectum, sigmoid and bladder D2cc, 1cc and 0.1cc respectively. The acute toxicity assessment was done using the RTOG scale. The follow-up was undertaken as per the institutional protocol and Mann-Whitney U-test were applied to compare the cohorts. Result(s): With a median follow-up of 6 months, the median CTV was D90%: 81.2 vs. 80.9 Gy and the median CTV volume was 44.3 vs 42.9 cc respectively. The 0.1 cm3 and 2 cm3 to bladder, rectum, and sigmoid were 105.6 vs 104.2 Gy and 85.5 vs 85.9Gy, 89.4Gy vs 88.7Gy and 69.1 vs 67.8Gy, and 84.7 vs 84.1Gy and 71.7 vs 69.9Gy, respectively suggesting no significant difference in the dosimetric outcomes with the two forms of applications. The less than three applications had a shorter overall treatment time with median OTT of 43 days vs. 55 days (p = 0.02). On completion of treatment and 6 months follow-up, local control was achieved in all patients. There was no significant difference in the acute toxicities in terms of cystitis and proctitis in both forms of the application. Conclusion(s): The single application/ twice application ICRT procedure showed similar outcomes as the traditional three-week duration treatment in terms of dosimetric outcomes and acute toxicities and ultimately leading to shortened overall treatment time. It also helped reduce the anesthesia burden and various resources associated with the procedure. Copyright © 2022
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Introduction: COVID -19 emerged in December 2019 in china and till date this virus has mutated into different strains which are somewhat different in their presentation and severity. Pakistan has faced five waves of COVID-19 till date. This study was aimed to compare Haematological parameters and outcomes of hospitalized patients during First and other waves (second and third) of COVID-19. Method(s): Demographic, Clinical and laboratory data as well as outcome of total 202 COVID-19 PCR positive patients admitted in Fatima memorial Hospital, Lahore, Pakistan was collected during first and other waves. Data of First wave is from May 2020 to July 2020, second wave from early November to Mid December 2020 and third wave from Mid march to June 2021. We compared the data on basis of SII as well hematological parameters of First Wave were compared with other waves (second & third) of COVID-19. Result(s): There were 54(26.7%) patients with SII< 600 and 148(73.2%) patients with SII>600. Neutrophilia (p-< 0.001), leukocytosis (p-< 0.001), lymphocytopenia(p-< 0.001), Raised NLR(p-< 0.001), PLR(p-< 0.001) and MLR(p-< 0.001) had direct association with SII. Raised SII was directly related to increased requirement of ventilator support (p-0.2) and Mortality (p-0.001). There were total 90(44.5%) patients in first wave and 112(55.4%) patients in other waves of COVID-19. More Females (33.3% Vs 57.1%) than Males (66.7% Vs 42.9%) were infected during other waves (p- 0.001). Anemia (27.8% vs 37.5%) (p-0.09), leucopenia (1.1% vs 8.9%) (p-< 0.001), Lymphocytopenia (20% Vs 39.3%) (p-0.003) and thrombocytopenia (3.3% Vs 25%) (p-< 0.001) were more prevalent in other waves of COVID-19 when compared to first wave. Requirement of Ventilator Support (7.7% vs 22%) and mortality (10% vs 33.9%) were also increased in other waves of COVID-19 Conclusion(s): Systemic immune Inflammation Index (SII) is a good predicting tool in COVID -19 patients for prognosis and is directly associated with severity of disease as well as outcome. Patients with cytopenias like anemia, leucopenia, lymphocytopenia thrombocytopenia, requirement of Ventilator Support and mortality were noted to be more in other waves of COVID-19. Haematological parameters like ANC, AMC NLR, PLR, MLR and SII show no significant difference between first and subsequent waves of COVID-19.
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INTRODUCTION: Extracorporeal membrane oxygenation (ECMO) has been utilized as a rescue therapy for patients with severe ARDS. Multiple case series have suggested that the duration of veno-venous ECMO support in patients with COVID-19 pneumonia may be longer than patients with ARDS secondary to alternative etiology. However, the impact of longer run of ECMO on patient outcomes are not clear. METHOD(S): This was a retrospective study performed at Mayo Clinic Florida and Mayo Clinic Rochester, tertiary ECMO centers in USA. Analysis includes all consecutive patients who were placed on VV ECMO for COVID-19- induced ARDS between January 2019 to March 2022. The study population was classified into two groups: short term ECMO duration (< 4 weeks) and prolonged ECMO support (>4 weeks). Demographic data, baseline clinical characteristics, treatments administered, mechanical ventilator data, lab data, ECMO data and outcome related data were collected and analyzed. RESULT(S): A total of 63 COVID-19 patients were included. For the entire cohort, the 30 day mortality was 6%, the 90 day mortality was 30% and the median duration of ECMO support was 35 days (IQR 38). A total of 6 (10%) patients went on to receive lung transplant. Among these, 25(40%) patients required ECMO for < 4 weeks and 38(60%) patients for >4 weeks. The median SOFA values (13 vs 11, 0.016) for the <=4 weeks cohort was higher. Both groups received similar COVID-19 therapies: glucocorticoids (96 vs 100%, p=0.397), tocilizumab (52 vs 50%, p=1.000), antivirals (88 vs 87%, p=1.000), and convalescent plasma (48 vs 45%, p=1.000). The cumulative mortality rates for the 2 groups were 8% vs 5% at 30 days (p=1.0), 12% vs 42% at 60 days (p=0.013), 12% vs 50% at 90 days (p=0.002) and 12% vs 50%(p=0.002) at 180 days. CONCLUSION(S): The study demonstrated that a substantial number of COVID19 patients require ECMO for > 4 weeks. In this cohort, the mortality rate in the first 4 weeks of ECMO support was low, at 6%. The patients who required ECMO for >4 weeks were more likely to have higher mortality compared to the patients treated with ECMO for shorter duration.
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Purpose: The on-going pandemic has impacted the use of anesthesia and the operating room frequency thereby affecting the brachytherapy treatment in various institutions due to the COVID-19 protocols. This has led to single applications of Intracavitary brachytherapy (ICRT) being used to deliver entire treatment boost in cervix cancer. We present our dosimetric and early clinical outcomes comparing traditional weekly three-fractions ICRT with single application/ two-applications ICRT Materials and Methods: In this retrospective analysis conducted in our department, a total of 39 cases, treated between January 2021 to January 2022 were evaluated for the study. Of these, 15 cases were treated with the traditional once a week applicator insertion for 3 fractions and 24 cases underwent lesser application - 20 cases underwent 2 insertions and 4 cases single insertion (all receiving total 3 fractions of 7Gy each). The dosimetric parameters were compared including CTV D90 and D95 along with rectum, sigmoid and bladder D2cc, 1cc and 0.1cc respectively. The acute toxicity assessment was done using the RTOG scale. The follow-up was undertaken as per the institutional protocol and Mann-Whitney U-test were applied to compare the cohorts. Results: With a median follow-up of 6 months, the median CTV was D90%: 81.2 vs. 80.9 Gy and the median CTV volume was 44.3 vs 42.9 cc respectively. The 0.1 cm3 and 2 cm3 to bladder, rectum, and sigmoid were 105.6 vs 104.2 Gy and 85.5 vs 85.9Gy, 89.4Gy vs 88.7Gy and 69.1 vs 67.8Gy, and 84.7 vs 84.1Gy and 71.7 vs 69.9Gy, respectively suggesting no significant difference in the dosimetric outcomes with the two forms of applications. The less than three applications had a shorter overall treatment time with median OTT of 43 days vs. 55 days (p = 0.02). On completion of treatment and 6 months follow-up, local control was achieved in all patients. There was no significant difference in the acute toxicities in terms of cystitis and proctitis in both forms of the application. Conclusion: The single application/ twice application ICRT procedure showed similar outcomes as the traditional three-week duration treatment in terms of dosimetric outcomes and acute toxicities and ultimately leading to shortened overall treatment time. It also helped reduce the anesthesia burden and various resources associated with the procedure.
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Virtual reality (VR) is gaining popularity these days for a variety of reasons, the most prominent of which is the Covid-19 scenario. This article outlines a strategy for restoring people's lives and allowing them to work from home, as well as bringing people together on a common platform to cheer them up. At Chulalongkorn University, the work technique was used to create a virtual three-dimensional (3D) chemistry lab. Many tactics were adopted and carried out step by step to provide a genuine experience of the lab when creating a virtual lab. Using Unity, a cross-platform game engine, the 3D model was then used to create an immersive and interactive VR experience. The final output is an immersive and interactive virtual reality environment with information constructed using Unity. © 2022 IEEE.
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The existing COVID-19 global epidemic has altered our lifestyles in different manners. It has created the need to always understand our position, which we have been seen in interaction with, as well as other specifics such as our body temp and to prevent the spread of such a viral infection. The above knowledge is especially important for students, as their yield to college tends to increase their occupational exposure. To solve this issue, several control systems must always be incorporated. Humans presently use thermoelectric detectors to search a person's temperature changes, card machines in bus routes to verify educators’ existence, and web platforms in which educators can register the attendance of the student for every class. Humans can use blockchain technology to connect and interact and develop an efficient, translucent COVID-19 tracking system. Throughout this paper, we start debating a fresh distributed ledgers traceability system that guarantees accountability among both students, schools, and the authorities to avoid virus spread and aid in interaction tracing. Utilizing blockchain technology and classroom Identity card, we support the implementation of the ancient nearby. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
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The coronavirus 2 illness (Covid-19) global pandemic has resulted in severe infection causing fever, cough, shortness of breath, pneumonia and even death. WHo is monitoring intimately in coordination with scientific experts and government agencies, the transmission rate of this virus and its neoteric variants identified worldwide. Since the start of year 2020, all the health authorities of each country are working in collaboration to explore the scientific information on coronavirus and providing essential guidelines to save humans. Undoubtedly, this pandemic impacted many lives regardless of all preventive steps followed to minimize its transmission. Currently, multiple anti Covid-19 vaccines are available everywhere and government authorities are monitoring and providing the guidelines for taking booster dose of vaccine to minimize and control the transmission of different variants of this virus. it is rational to state that some of the available anti Covid-19 vaccines may not be highly efficient against new emerging variants so further investigation and research are the need of hour. Therefore, the present review portrayed the features of the novel variants and mutations of coronavirus 2 (Covid-19) and therapeutic updates associated with the effectiveness of different vaccines against new strains reported worldwide. Copyright © 2022 Oriental Scientific Publishing Company. All rights reserved.
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The plant Curcuma longa, a perennial herbaceous member of the Zingiberaceae (ginger family), produces turmeric. Protein, fat, minerals, carbs, and moisture are all included in turmeric. Curcumin (diferuloylmethane), a phenolic diketone that makes up 34 percent of curcumin and is made up of curcumin I, curcumin II, and curcumin III, is what gives turmeric its characteristic yellow colour. Curcumin have versatile pharmacotherapeutic potential and their biological functions have been thoroughly investigated in recent years. As the main bioactive component, curcumin has numerous pharmacological properties including antioxidant, anti-inflammatory, anti-hypertensive, anti-diabetic, hepatoprotective, anti-rheumatoid arthritis and anti-cancer properties. In persons who are active, it improves recuperation and performance. It helps with viral infections and dental issues such as dental pain, gingivitis. Covid also benefits from curcumin. ar-turmerone also possesses antiinflammatory properties. Ar-turmerone is a potentially effective treatment for a number of neurologic conditions like schizophrenia. Multiple health advantages are provided by curcumin when mixed with boosting agents. Copyright © 2022, Global Research Online. All rights reserved.
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Coronavirus disease 2019 (COVID-19) is an infectious disease that has spread globally, disrupting the health care system and claiming millions of lives worldwide. Because of the high number of Covid-19 infections, it has been challenging for medical professionals to manage this crisis. Estimating the Covid-19 percentage can help medical staff categorize patients by severity and prioritize accordingly. With this approach, the intensive care unit (ICU) can free up resuscitation beds for the critical cases and provide other treatments for less severe cases to efficiently manage the healthcare system during a crisis. In this paper, we present a transformer-based method to estimate covid-19 infection percentage for monitoring the evolution of the patient state from computed tomography scans (CT-scans). We used a particular Transformer architecture called Swin Transformer as a backbone network to extract the feature from the CT slice and pass it through multi-layer perceptron (MLP) to obtain covid-19 infection percentage. We evaluated our approach on the covid-19 infection percentage estimation challenge dataset, annotated by two expert radiologists. The experimental results show that the proposed method achieves promising performance with a mean absolute error (MAE) of 4.5042, Pearson correlation coefficient (PC) of 0.9490, root mean square error (RMSE) of 8.0964 on the given Val set leaderboard and a MAE of 3.5569, PC of 0.8547 and RMSE of 7.5102 on the given Test set Leaderboard. These promising results demonstrate the high potential of Swin Transformer architecture for this image regression task of covid-19 infection percentage estimation from CT-scans. The source code of this project can be found at: https://github.com/suman560/Covid-19-infection-percentage-estimation. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.